Testosterone

Testosterone replacement options are the optional treatment or replacement techniques available to treat and retreat testes and testosterone levels in the body when they are prone to disorders.

Before learning testosterone replacement options, let's look into what testosterone is and understand how it works.

Testosterone is the essential hormone for the male genital to stay erect during sexual intercourse, eject semen at the proper time during sexual activity, and first most, maintain sexual intention and libido in the male body.

Testosterone has many beneficial effects that include increase bone strength and density, induce hematopoiesis, drive sexual function and libido, providing a cardioprotective effect and increase muscle strength.

Testosterone levels are mandated to male body behaviour. Due to any disorder, testosterone levels could be found less than the required resulting in less sperm count, Erectile Dysfunction.

Few men may fall deficient in testosterone levels resulting in various malfunctions right through sexual point of view and physical point of view. 

Hypogonadism is the typical name given to the low testosterone in the male. 

Low testosterone can result from genes and genetic orders, the natural failure. It could be the result of male various actions being unconscious about body and health. Low testosterone results in its subdues that he out-of-control reasons can be cured and the controlled actions can be prevented.

There are ways to retain testosterone levels in the body right through medication, exercise, water supply, and food supplements.

Zinc and magnesium are the necessary minerals to maintain testes and their secretion. Vitamin D is an essential need to balance testosterone hormone levels. 

Fruits like papaya, mango, pomegranate, grapes, bananas are essential to maintain testosterone levels. Milk, meat, leafy vegetables, and eggs are the needed protein supplements.

Ashwagandha, Puncturevine, Epimedium, Yohimbe bark, garlic, and Pine bark extract are few of the Ayurvedic Supplements that coordinate with testes gland secretions.

Other than mineral supplements, food supplements and ayurvedic supplements, there are few options to treat low testosterone syndrome which is named after testosterone replacement therapy.

Testosterone Replacement Therapy

Testosterone replacement therapy (TRT) is a well known treatment for men with symptomatic hypogonadism.

The testosterone replacement therapy is also named as androgen replacement therapy for androgen plays a major role in the displacement of testosterone hormone.

The benefits from testosterone replacement therapy are increased libido and energy level, beneficial effects on bone density, strength and muscle as well as cardioprotective effects.

Men on testosterone replacement therapy should be aware of side-effects such as polycythemia, peripheral edema, cardiac and hepatic dysfunction.

Oral Testosterone Undecanoate

New oral testosterone therapy offers men with certain forms of hypogonadism a novel formulation that reduces the dietary-fat effect and variability of testosterone response observed with previous oral formulations.

Oral testosterone undecanoate, approved by the FDA is the first new oral testosterone replacement product in more than 60 years. The drug is indicated for men with low testosterone levels due to specific medical conditions, such as Klinefelter syndrome or tumors that have damaged the pituitary gland.

Oral testosterone undecanoate contains a boxed warning on its label stating that the drug can cause hypertension, increasing cardiovascular risk. Health care providers should consider a patient’s individual CV risks and ensure that blood pressure is adequately controlled before prescribing oral testosterone undecanoate, according to the FDA; they should also periodically monitor patient BP during treatment.

Oral testosterone undecanoate should not be used to treat men with age-related hypogonadism, in which testosterone levels decline due to aging, even if these men have symptoms that appear to be related to low testosterone, according to the FDA, which stated that the drug’s benefits do not outweigh its risks for that use.

Testosterone Nasal Gel

The first approved intranasal testosterone gel offers men with hypogonadism a unique formulation that promises rapid absorption and onset of action with lower adverse effects.

Testosterone nasal gel (Natesto, Aytu BioScience) was approved by the FDA in 2014 for use in men with primary or hypogonadotropic hypogonadism, congenital or acquired, and is self-administered via a nasal applicator, minimizing the risks of secondary exposure to testosterone by women or children.

Testosterone Enanthate Injection

The testosterone enanthate injection (Xyosted, Antares Pharma Inc.), approved by the FDA in October, is available in 50-mg, 75-mg and 100-mg doses in a single-use, disposable QuickShot injection device for use at home.

This therapy provides consistent, stable testosterone levels, easy, painless injections and very high patient satisfaction without the mess of gels or the pain of pellets,

The subcutaneous dosing of testosterone enanthate also removes transfer concerns commonly associated with gels and potentially reduces the need for in-office injection procedures that may require more frequent patient visits.

The most commonly observed adverse effects were an increase in hematocrit and hypertension

Testosterone enanthate has a boxed warning alerting patients and prescribers to possible increases in BP that can lead to CV events.

Take Away

The testosterone hormone levels could be greatly impacted with daily exercises and yoga. Kundalini yoga is the best practice to develop strong force in the testes glands and androgen glands resulting in an increased level of testosterone.